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Seco-Lupane Triterpene Derivatives Induce Ferroptosis through GPX4/ACSL4 Axis and Target Cyclin D1 to Block the Cell Cycle | Journal of Medicinal Chemistry
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Frontiers | Inhibition of Acyl-CoA Synthetase Long-Chain Family Member 4 Facilitates Neurological Recovery After Stroke by Regulation Ferroptosis
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JCI - RB1-deficient prostate tumor growth and metastasis are vulnerable to ferroptosis induction via the E2F/ACSL4 axis
Functional Interaction between Acyl-CoA Synthetase 4, Lipooxygenases and Cyclooxygenase-2 in the Aggressive Phenotype of Breast Cancer Cells | PLOS ONE
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Activation of ALOX12 by a multi-organelle-orienting photosensitizer drives ACSL4-independent cell ferroptosis | Cell Death & Disease
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ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition. - Abstract - Europe PMC
![Model of ferroptosis and key molecules in the adrenal cortex. ACSL4... | Download Scientific Diagram Model of ferroptosis and key molecules in the adrenal cortex. ACSL4... | Download Scientific Diagram](https://www.researchgate.net/publication/339994050/figure/fig3/AS:870280117366787@1584502357253/Model-of-ferroptosis-and-key-molecules-in-the-adrenal-cortex-ACSL4-catalyzes-activation.png)
Model of ferroptosis and key molecules in the adrenal cortex. ACSL4... | Download Scientific Diagram
Fatty acid activation in carcinogenesis and cancer development: Essential roles of long‑chain acyl‑CoA synthetases (Review)
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The primary mechanism of ferroptosis. ACSL4 acylates PUFA, which is... | Download Scientific Diagram
![PKCβII phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis | Nature Cell Biology PKCβII phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis | Nature Cell Biology](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41556-021-00818-3/MediaObjects/41556_2021_818_Fig7_HTML.png)
PKCβII phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis | Nature Cell Biology
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ACSL4, PUFA, and ferroptosis: new arsenal in anti-tumor immunity | Signal Transduction and Targeted Therapy
![Frontiers | ACSL4 as a Potential Target and Biomarker for Anticancer: From Molecular Mechanisms to Clinical Therapeutics Frontiers | ACSL4 as a Potential Target and Biomarker for Anticancer: From Molecular Mechanisms to Clinical Therapeutics](https://www.frontiersin.org/files/Articles/949863/fphar-13-949863-HTML/image_m/fphar-13-949863-g001.jpg)
Frontiers | ACSL4 as a Potential Target and Biomarker for Anticancer: From Molecular Mechanisms to Clinical Therapeutics
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Role of long-chain acyl-CoA synthetase 4 in formation of polyunsaturated lipid species in hepatic stellate cells - ScienceDirect
![Schematic model of the signaling pathway involved in ACSL4-induced up-regulation of intramitochondrial AA, LOX products, COX-2 and PGE2 production in the development of an aggressive phenotype in breast cancer cells. Schematic model of the signaling pathway involved in ACSL4-induced up-regulation of intramitochondrial AA, LOX products, COX-2 and PGE2 production in the development of an aggressive phenotype in breast cancer cells.](https://s3-eu-west-1.amazonaws.com/ppreviews-plos-725668748/819655/preview.jpg)